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Bacterial Outer Membrane Vesicles. Mediators of virulence and

J Clin Microbiol 1990; 28:2674. Although a number of putative M. catarrhalis virulence factors have been identified and described in detail, (128) showed that colony morphology, Gram stain, and. Moraxella catarrhalis is a common cause of lower respiratory tract infection in adults with chronic obstructive pulmonary disease (COPD). The antibody response to outer membrane protein (OMP) CD, a highly conserved surface protein of M. catarrhalis under consideration as a vaccine antigen, was studied in adults with COPD following 40 episodes of infection or colonization.

cinereus) were identified as M. catarrhalis (Neisseria catarrhalis); sometimes N. cinerea isolates were recognized as belonging to a colonial morphologic subtype of M. catarrhalis (Neisseria catarrhalis). M. catarrhalis is the most important pathogen of this genus (Table 308-2). Pathobiology. The organism is isolated exclusively from humans and is found predominantly in the respiratory tract. M. catarrhalis adheres to mucosal cells with the aid of pili.

Moraxella catarrhalis is classified with the genera Neisseria, Moraxella, Kingella, and Acinetobacter in the family Neisseriaceae. The taxonomic position of M. catarrhalis is currently being debated; it has been proposed that M. catarrhalis be assigned to the genus Moraxella (M. catarrhalis) in the family Moraxellaceae, or to its own genus, Branhamella, in the family Branhamaceae.

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Bacterial Strains. The identity of an isolate as M. catarrhalis was confirmed by colony morphology and the presence of butyrate esterase Studies have shown that M catarrhalis colonizes the upper respiratory tract in 28-100% of humans in the first year of life. In adults, the colonization rate is 1-10.4%. Colonization appears to be Study Neisseria and Moraxella Catarrhalis Flashcards at ProProfs - Neisseria and Moraxella Catarrhalis epidemiology, morphology, culture characteristics, diagnostic biochemical tests, and serology.

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Moraxella catarrhalis. Terms.

The organisms are short rods, coccobacilli, or as in the case of Moraxella catarrhalis, diplococci in morphology, with asaccharolytic, oxidase -positive, and catalase -positive properties. M. catarrhalis is the clinically most important species under this genus. Moraxella spp. are Gram-negative diplococci that morphologically and phenotypically resemble Neisseria spp. They are strictly aerobic, oxidase-positive, catalase-positive, DNAse-positive and asaccharolytic.
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Infection is believed to result from contiguous spread of the organism from sites of M. catarrhalis is the third most common bacterial agent in pediatric acute otitis media and maxillary sinusitis – surpassed only by Streptococcus pneumoniae and Haemophilus influenzae . In adult patients, M. catarrhalis is responsible for acute exacerbations of chronic bronchitis and bronchopneumonia in the elderly and immune compromised .

24 hours, 37°C inan aerobic atmosphere enriched with 5% carbon dioxide.
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M. catarrhalis forms a “hockey puck”-like colony which may be nudged across the plate intact with a bacteriological loop.2 QUALITY CONTROL All lot numbers of Catarrhalis Selective Medium have been tested using the following quality control organisms and have been found to be acceptable. Gonorrheae clinical infections in males. - incubation 2-7 days.